Why does Kendamil use whole milk fats?

Why does Kendamil use whole milk fats?

Most infant formulas worldwide rely on a blend of various vegetable oils to provide the necessary fat content. Common vegetable oils used in formula production include coconut oil, corn oil, palm oil, soya oil, sunflower oil, high oleic safflower oil, and rapeseed (canola) oil. The widespread use of vegetable oils is largely due to their cost-effectiveness and ability to increase the polyunsaturated fat content in formulas. However, Kendamil takes a different approach, choosing mammalian milk fat over vegetable oils for several significant reasons.

One of the primary reasons Kendamil prioritises real milk fat is that it closely mirrors the fat profile of human breast milk, unlike vegetable oils. Milk fat contains a unique structure known as the Milk Fat Globule Membrane (MFGM), which consists of glycoproteins, enzymes, and lipids like phospholipids and sphingolipids. MFGM plays a vital role in infant nutrition as it emulsifies fats for easier digestion and provides bioactive components that are naturally present in breast milk but absent from vegetable oils. Industrially processed vegetable oils often require synthetic emulsifiers, such as soya lecithin, to achieve a similar function.

Clinical studies underscore the benefits of MFGM for infants. Research has shown that MFGM supplementation improves brain development, with one study highlighting increased serum choline levels in infants aged 2–6 months—a critical factor for brain function and growth. Other findings demonstrate improved cognitive development in infants between 6–12 months. Additionally, MFGM enhances neurodevelopment and overall health, with evidence from The Journal of Paediatrics showing improved language skills, fewer cases of diarrhoea, and reduced respiratory infections in infants consuming MFGM-enriched formulas. Moreover, components of MFGM like osteopontin and lactadherin are essential for immune regulation, promoting gut epithelial repair, reducing intestinal inflammation, and lowering the risk of infections such as otitis media.

The fatty acid profiles in mammalian milk and vegetable oils differ significantly. Although fats in human milk, bovine milk, and vegetable oils are primarily triglycerides, their fatty acid compositions vary. Human and bovine milk fat contain short and medium-chain fatty acids (C4:0 to C12:0), which are highly digestible and beneficial for infants. Mammalian milk also features nearly 400 unique fatty acids, far exceeding the diversity found in vegetable oils, which often lack short-chain fatty acids. Vegetable oil blends attempt to mimic the complexity of human milk but fail to match its natural balance and digestibility.

Palmitic acid, a crucial fatty acid in infant nutrition, further highlights the differences between mammalian milk and vegetable oils. In mammalian milk, palmitic acid is predominantly positioned at the sn-2 position of the triglyceride, enhancing its absorption. In contrast, vegetable oils like palm oil place palmitic acid at the sn-1 or sn-3 positions, making it harder to absorb. This difference can lead to calcium binding in the gut, forming hard soaps that contribute to constipation, hard stools, and bone demineralisation. A randomised study published in Paediatrics confirmed that infants fed palm oil-based formulas exhibited reduced bone mineralisation, underscoring the limitations of vegetable oil in meeting infant nutritional needs.

Cholesterol also plays a vital role in infant development. It supports brain growth, myelination, steroid hormone production, and fatty acid absorption. Unlike vegetable oil-based formulas, which are largely cholesterol-free, both human and bovine milk naturally contain cholesterol. This makes milk fat a superior choice for infant formulas, as it aligns more closely with the natural composition of breast milk.

Recent studies reinforce the benefits of using whole milk fat in formulas. Research published in the Asian Pacific Journal of Paediatrics found that infants fed milk-fat-based formulas experienced less gut discomfort, reduced crying and fussiness, and fewer calcified soap products in their stools. A meta-analysis in the American Journal of Clinical Nutrition, involving over 20,000 children, further linked whole milk consumption to a lower risk of childhood obesity compared to low-fat alternatives.

At Kendamil, the use of whole bovine and caprine milk fat reflects a commitment to providing formulas that closely resemble the natural composition of human breast milk. Whole milk fat offers a superior fatty acid profile, naturally includes essential bioactive components like MFGM and cholesterol, and supports better digestion, reduced discomfort, and healthier growth outcomes. Unlike manufacturers that rely on skimmed milk and vegetable oils, Kendamil uses full-fat milk sourced from local, sustainable farms. This approach minimises processing steps, preserving the quality and integrity of the milk while delivering optimal nutrition for infants.

References

  1. World Health Organization. Breastfeeding. Available at: https://www.who.int/health-topics/breastfeeding#tab=tab_1.

  2. EU Project Contract N. SPC 2002359. Protection, promotion and support of breastfeeding in Europe: A blueprint for action. Accessed at: https://ec.europa.eu/health/ph_projects/2002/promotion/fp_promotion_2002_frep_18_en.pdf.

  3. Breastfeeding and the Use of Human Milk. Pediatrics. March 2012; 129(3): e827-e841. doi: 10.1542/peds.2011-3552.

  4. Manson WG, Weaver LT. Fat digestion in the neonate. Archives of Disease in Childhood - Fetal and Neonatal Edition. 1997; 76: F206-F211.

  5. Jensen RG, Ferris AM, Lammi-Keefe CJ, Henderson RA. Lipids of bovine and human milks: a comparison. J Dairy Sci. 1990 Feb;73(2):223-40. doi: 10.3168/jds.S0022-0302(90)78666-3.

  6. Berger A, Fleith M, Crozier G. Nutritional implications of replacing bovine milk fat with vegetable oil in infant formulas. J Pediatr Gastroenterol Nutr. 2000 Feb;30(2):115-30. doi: 10.1097/00005176-200002000-00006.

  7. Innis SM. Dietary triacylglycerol structure and its role in infant nutrition. Advances in Nutrition. 2011; 2(3):275–283. doi: 10.3945/an.111.000448.

  8. Zou X, Guo Z, Jin Q, et al. Composition and microstructure of colostrum and mature bovine milk fat globule membrane. Food Chem. 2015;185:362-70. doi: 10.1016/j.foodchem.2015.03.145.

  9. Dewettinck K, Rombaut R, Thienpont N, et al. Nutritional and technological aspects of milk fat globule membrane material. International Dairy Journal. 2008;18:436-457. doi: 10.1016/j.idairyj.2007.10.014.

  10. Contarini G, Povolo M. Phospholipids in milk fat: composition, biological and technological significance, and analytical strategies. Int J Mol Sci. 2013;14:2808-2831. doi: 10.3390/ijms14022808.

  11. Delplanque B, Gibson R, Koletzko B, et al. Lipid quality in infant nutrition. J Pediatr Gastroenterol Nutr. 2015;61(1):8-17. doi: 10.1097/MPG.0000000000000818.

  12. He X, Parenti M, Grip T, et al. Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine supplemented formula: a randomized controlled trial. Sci Rep. 2019;9:339. doi: 10.1038/s41598-018-36292-5.

  13. Timby N, Domellöf E, Hernell O, et al. Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: A randomized controlled trial. Am J Clin Nutr. 2014;99:860-868. doi: 10.3945/ajcn.113.064295.

  14. Gallier S, MacGibbon AKH, McJarrow P. Milk fat globule membrane (MFGM) supplementation and cognition. Agro FOOD Ind. Hi-Tech. 2018;29:14-16.

  15. Li F, Wu SS, Berseth CL, et al. Improved neurodevelopmental outcomes associated with bovine milk fat globule membrane and lactoferrin in infant formula: A randomized, controlled trial. J Pediatr. 2019 Dec;215:24-31.e8. doi: 10.1016/j.jpeds.2019.08.030.

  16. Brink LR, Lönnerdal B. Milk fat globule membrane: the role of its various components in infant health and development. J Nutr Biochem. 2020;85:108465. doi: 10.1016/j.jnutbio.2020.108465.

  17. Lee H, Padhi E, Hasegawa Y, et al. Compositional dynamics of the milk fat globule and its role in infant development. Front Pediatr. 2018;6:313. doi: 10.3389/fped.2018.00313.

  18. Juvarajah T, Wan-Ibrahim WI, Ashrafzadeh A, et al. Human milk fat globule membrane contains hundreds of abundantly expressed and nutritionally beneficial proteins that are generally lacking in caprine milk. Breastfeed Med. 2018;13:631-637. doi: 10.1089/bfm.2018.0057.

  19. Timby N, Hernell O, Vaarala O, et al. Infections in infants fed formula supplemented with bovine milk fat globule membranes. J Pediatr Gastroenterol Nutr. 2015;60(3):384-9. doi: 10.1097/MPG.0000000000000624.

  20. Hageman J, Danielsen M, Nieuwenhuizen A, et al. Comparison of bovine milk fat and vegetable fat for infant formula: Implications for infant health. International Dairy Journal. 2019;92. doi: 10.1016/j.idairyj.2019.01.005.

  21. Dorni C, Sharma P, Saikia G, Longvah T. Fatty acid profile of edible oils and fats consumed in India. Food Chem. 2018;238:9-15. doi: 10.1016/j.foodchem.2017.05.072.

  22. Innis SM. Palmitic acid in early human development. Crit Rev Food Sci Nutr. 2016;56(12):1952-1959. doi: 10.1080/10408398.2015.1018045.

  23. Bracco U. Effect of triglyceride structure on fat absorption. Am J Clin Nutr. 1994;60(6):1002S-1009S. doi: 10.1093/ajcn/60.6.1002S.

  24. López-López A, López-Sabater M, Campoy-Folgoso C, et al. Fatty acid and sn-2 fatty acid composition in human milk from Granada (Spain) and in infant formulas. Eur J Clin Nutr. 2002;56:1242-1254. doi: 10.1038/sj.ejcn.1601470.

  25. Qi C, Sun J, Xia Y, et al. Fatty acid profile and the sn-2 position distribution in triacylglycerols of breast milk during different lactation stages. J Agric Food Chem. 2018;66(12):3118-3126. doi: 10.1021/acs.jafc.8b01085.